GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE46071 Query DataSets for GSE46071
Status Public on Apr 10, 2014
Title Linezolid Exerts Greater Bacterial Clearance but No Modification of Host Lung Gene Expression Profiling: a Mouse MRSA Pneumonia Model
Organism Mus musculus
Experiment type Expression profiling by array
Summary Using the stringent criteria (fold change ≥ 1.5 up or down, P < 0.01, FDR < 0.05) to filter significantly differentially expressed genes, we did not identify any genes whose expression levels were significantly different between the PBS and PBS+LZD groups or between the LAC and LAC+LZD at Day 1 or Day 3 post MRSA infection. However, a remarkable difference was demonstrated (Figure 5A) between PBS and LAC groups at either Day 1 or Day 3 post MRSA infection.
Overall design Four independent mouse lung tissue samples at Day 1 and Day 3 post MRSA infection with and without Linezolid therapy were randomly selected from each group for microarray analysis.
Contributor(s) Chen J, Feng G, Song Y, Wardenburg JB, Lin S, Inoshima I, Otto M, Wunderink RG
Citation(s) 23826353
Submission date Apr 15, 2013
Last update date Aug 23, 2019
Contact name Jiwang Chen
Organization name University of Illinois at Chicago
Street address 840 S Wood Street
City Chicago
State/province IL
ZIP/Postal code 60612
Country USA
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (24)
GSM1120503 Day 1 post PBS mock sample 1
GSM1120504 Day 1 post PBS mock sample 2
GSM1120505 Day 1 post PBS mock sample 3
BioProject PRJNA200955

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46071_RAW.tar 3.1 Mb (http)(custom) TAR
Raw data included within Sample table
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap