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Status |
Public on Sep 25, 2013 |
Title |
Effects of Brazilian propolis on gene expression of stromal cells in mesenteric adipose tissue of ob/ob mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
A hive product propolis has been used for folk medicine for more than 4, 000 years. So far, several line of studies demonstrated that propolis improved glucose metabolism in obese models. In this study, we inverstigated whether propolis modulates stromal cells of mesenteric adipose tissue of ob/ob mice.
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Overall design |
Male ob/ob mice were inhjected with Brazilian propolis ethanol extract (100mg/kg ip, twice a week) or vehicle for 12 weeks. Subsequently, vasucular stromal fraction was prepared from mesenteric adipose tissue. Total cellular RNA extracted from the fraction was used for microarray analysis. Biological triplicates were subjected.
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Contributor(s) |
Kitamura H, Naoe Y |
Citation(s) |
24052898 |
Submission date |
Apr 16, 2013 |
Last update date |
Feb 02, 2018 |
Contact name |
Hiroshi Kitamura |
E-mail(s) |
ktmr@rakuno.ac.jp
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Phone |
81-11-388-4781
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Organization name |
Rakuno Gakuen University
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Department |
School of Veterinary Medicine
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Lab |
Laboratory for Veterinary Physiology
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Street address |
582 Midorimachi, Bunkyodai
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City |
Ebetsu |
ZIP/Postal code |
069-8501 |
Country |
Japan |
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Platforms (1) |
GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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Samples (6)
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GSM1123902 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with vehicle for 12 wks, biological rep 1 |
GSM1123903 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with vehicle for 12 wks, biological rep 2 |
GSM1123904 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with vehicle for 12 wks, biological rep 3 |
GSM1123905 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with propolis for 12 wks, biological rep 1 |
GSM1123906 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with propolis for 12 wks, biological rep 2 |
GSM1123907 |
vascular stromal fraction of mesenteric adipose tissue of ob/ob mice, treated with propolis for 12 wks, biological rep 3 |
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Relations |
BioProject |
PRJNA197284 |