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Series GSE46418 Query DataSets for GSE46418
Status Public on Apr 27, 2013
Title Comparative transcriptome analysis of Brucella melitensis 16M and its hfq mutant under acidified minimum medium (GEM4.0) conditions
Platform organism Brucella melitensis bv. 1 str. 16M
Sample organism Brucella melitensis
Experiment type Expression profiling by array
Summary Hfq is a bacterial Sm-like protein which serves as a post-transcriptional regulator of global gene expression. It has been shown to be involved in a wide range of cellular processes and pathways. To characterize the regulation roles of Hfq in Brucella melitensis, the in vitro hfq induction conditions simulating intracellular environments were firstly defined, and then, the transcriptome of the hfq mutant was compared to that of the wild type strain. Comparative transcriptome analysis showed that a total of 359 genes showed a>2.0-fold change in transcript abundance in Δhfq when compared to that in 16M.
 
Overall design 2 wild type samples and 2 hfq mutant samples were analyzed.
 
Contributor(s) Wang Y, Chen Z, Wang T
Citation(s) 23977181
Submission date Apr 26, 2013
Last update date Nov 08, 2013
Contact name tai 2006
E-mail(s) qinshihuang320@163.com
Organization name Department of Infectious Disease Control, Institute of Disease Control and Prevention, Academy of Military Medical Sciences
Street address Dongdajie
City Beijing
ZIP/Postal code 100071
Country China
 
Platforms (1)
GPL11117 Brucella 16M whole genome microarray
Samples (4)
GSM1129940 16MΔhfq(CY5)-16M(CY3), rep1
GSM1129941 16MΔhfq(CY3)-16M(CY5), rep1
GSM1129942 16MΔhfq(CY5)-16M(CY3), rep2
Relations
BioProject PRJNA200305

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46418_RAW.tar 2.4 Mb (http)(custom) TAR (of GPR)
Processed data included within Sample table

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