|
| Status |
Public on Dec 28, 2013 |
| Title |
Genome-wide parent-of-origin DNA methylation analysis [Methyl-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
Genomic imprinting is a form of epigenetic regulation that results in expression of either the maternally or paternally inherited allele of a subset of genes. Imprinted loci contain differentially methylated regions (DMRs) where cytosine methylation marks one of the parental alleles, providing cis-acting regulatory elements that influence the allelic expression of surrounding genes, however to date the total number of imprinted loci within the human genome is unknown. To characterize known imprinted DMRS and identify novel imprinted loci we have performed whole-genome bisulphite sequencing and high-resolution DNA methylation array analysis of healthy tissues.
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| |
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| Overall design |
Sequencing of bisulfite converted DNA analysis of normal brain (white matter), liver and term placenta tissue
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| |
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| Contributor(s) |
Monk D, Esteller M |
| Citation(s) |
24402520 |
| Submission date |
May 07, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Manel Esteller |
| Organization name |
IDIBELL
|
| Department |
PEBC
|
| Lab |
Cancer Epigenetics
|
| Street address |
Hospital Duran i Reynals Av. Gran Via s/n km, 2.7
|
| City |
L'Hospitalet de Llobregat |
| State/province |
Barcelona |
| ZIP/Postal code |
08908 |
| Country |
Spain |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE52578 |
Genome-wide parent-of-origin DNA methylation analysis |
|
| Relations |
| BioProject |
PRJNA201856 |
| SRA |
SRP022149 |
