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Series GSE46844 Query DataSets for GSE46844
Status Public on May 11, 2013
Title Expression data of kidney multiciliated cells from zebrafish embryos
Organism Danio rerio
Experiment type Expression profiling by array
Summary Multiciliated cells (MCCs) possess multiple motile cilia on the cell surface and are widely distributed throughout the vertebrate body to perform important physiological functions by regulating fluid movement in the intercellular space. However, neither their function during organ development nor the molecular mechanisms underlying multiciliogenesis are yet well understood. We aim to study the function of miR-34b in multiciliogenesis.
We used microarrays to study the global gene expression change in multiciliated cells after miR-34b knockdown.
Overall design Multiciliated cells were isolated from 3 dpf control embryos (injected with control morpholino) and miR-34b morphants (injected with miR-34b morpholino) for RNA extraction and hybridization on Affymetrix microarrays. Two independent sets of biological replicates were used.
Contributor(s) Wang L, Zhou Y
Citation(s) 23698347
Submission date May 10, 2013
Last update date Jan 25, 2018
Contact name Lei Wang
Organization name Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Street address Room 408, Building 1 225 South Chong Qing Road
City Shanghai
ZIP/Postal code 200025
Country China
Platforms (1)
GPL1319 [Zebrafish] Affymetrix Zebrafish Genome Array
Samples (4)
GSM1139092 Multiciliated cell_control_rep1
GSM1139093 Multiciliated cell_control_rep2
GSM1139094 Multiciliated cell_miR-34B morphants_rep1
BioProject PRJNA202452

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE46844_RAW.tar 7.7 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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