|
| Status |
Public on May 18, 2013 |
| Title |
The genetic basis for differential macrophage activation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Differential macrophage activation mediate genetic differences to a variety of inflammatory pathologies. We wanted to elucidate the transcriptional and regulatory programs regulating differential macrophage activation in genetically diverse mouse strains.
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| Overall design |
Bone marrow-derived macrophages (BMDMs) from AJ and C57BL/6j mice were left unstimulated, stimulated with IFN/TNF, or IL-4, or CpG, or LPS or IFN/TNF and infected with a type II (Pru A7) strain of Toxoplasma gondii, or infected with Pru A7 and gene expression analyzed 18 hrs later.
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| |
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| Contributor(s) |
Hassan MA, Jensen KD, Saeij JP |
| Citation(s) |
26510153 |
| Submission date |
May 17, 2013 |
| Last update date |
Jan 13, 2021 |
| Contact name |
Musa Hassan |
| Organization name |
University of Edinburgh
|
| Department |
Roslin
|
| Lab |
Hassan
|
| Street address |
Easter Bush
|
| City |
Edinburgh |
| State/province |
Scotland |
| ZIP/Postal code |
EH25 9RG |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL8321 |
[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array |
|
| Samples (16)
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| Relations |
| BioProject |
PRJNA203364 |
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