|
| Status |
Public on Jun 13, 2013 |
| Title |
Effect of ETV1 knockdown on genome wide AR binding in LNCaP Cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Translocation of ETS transcription factors including ERG and ETV1 occur in half of all prostate cancers. LNCaP cells harbor an ETV1 translocation. We performed ChIP-Seq analysis to determine the role of ETV1 on AR binding. The localization of enhancers were determined by H3K4me1 ChIP-Seq.
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| |
|
| Overall design |
To determine ETV1 and H3K4me1 localization, logarithmically growing cells
|
| |
|
| Contributor(s) |
Chen Y, Sawyers CL |
| Citation(s) |
23817021 |
| Submission date |
May 20, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Yu Chen |
| E-mail(s) |
cheny1@mskcc.org
|
| Phone |
646-888-3356
|
| Organization name |
Memorial Sloan Kettering Cancer Center
|
| Department |
Human Oncology and Pathogenesis Program
|
| Lab |
Chen
|
| Street address |
1275 York Ave, Box 20
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
|
| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE47220 |
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss |
|
| Relations |
| BioProject |
PRJNA203679 |
| SRA |
SRP022924 |
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