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Series GSE47542 Query DataSets for GSE47542
Status Public on Dec 31, 2013
Title IMR90 lung fibroblasts treated with IL-4 or IL-13
Organism Homo sapiens
Experiment type Expression profiling by array
Summary IL-4 and IL-13 are cytokines involved in type 2 immune responses involved in atopic asthma and other diseases. They have a partially overlapping set of cognate receptors whose roles are incompletely understood. Here we explore the effects of these cytokines on lung fibroblasts in order to assess the global similarities and contrasts in the genes whose expression their ligation modulates.
 
Overall design IMR-90 lung fibroblast cells were cultured on matrigel or plastic and treated for 24 hours with IL-4 (10 ng/ml), IL-13 (10ng/ml), or TNFa (10 ng/ml) before harvest.
 
Contributor(s) Abbas AR, Arron JR, Chandriani S
Citation(s) 24879793
Submission date May 30, 2013
Last update date Jan 23, 2019
Contact name Alex Abbas
E-mail(s) abbas@gene.com
Organization name Genentech, Inc.
Department Bioinformatics
Street address 1 DNA Way
City South San Francisco
State/province CA
ZIP/Postal code 94080
Country USA
 
Platforms (1)
GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Samples (24)
GSM1151928 unstim_matrigel_rep1
GSM1151929 IL4_matrigel_rep1
GSM1151930 IL4_matrigel_rep2
Relations
BioProject PRJNA206009

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE47542_RAW.tar 105.1 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table

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