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| Status |
Public on Sep 22, 2013 |
| Title |
Effect of progerin on p53-deficient vascular smooth muscle cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of p53-deficient (E6-expressing) human vascular smooth muscle cells (VSMCs) that express progerin, a mutated form of lamin A resposible for Hutchinson- Gilford progeria syndrome (HGPS). p53 pathway is associated with HGPS. Results provide insight into molecular mechanisms underlying vascular dysfunction of HGPS caused by other than p53 pathway.
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| |
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| Overall design |
The gene expression of VSMCs induced to express E6 and either lamin A or progerin by retroviral vectors.
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| |
|
| Contributor(s) |
Yamashita M, Sato K, Kinoshita D |
| Citation missing |
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| Submission date |
May 31, 2013 |
| Last update date |
Jan 09, 2018 |
| Contact name |
Daisuke Kinoshita |
| E-mail(s) |
d.kinoopyg.0722@gmail.com
|
| Organization name |
Chiba University
|
| Street address |
1-8-1 Inohana, Chuo-ku
|
| City |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL13497 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA206061 |
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