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| Status |
Public on Apr 02, 2015 |
| Title |
Tumor-educated circulating monocytes are powerful specific biomarkers for diagnosis of colorectal cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of tumor-educated changes in peripheral blood monocytes at the gene expression level. We analyzed if gene expression in monocytes of patients with colorectal cancer is differential from those of healthy volunteers and found a diagnostic signature that allowed to accurately discriminate patients with colorectal cancer from healthy individuals.
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| Overall design |
Peripheral blood monocytes from 93 distinct individuals are profiled on 8 beadchips. The individuals belong to one of three groups: healthy volunteers (38), patients with non-metastatic colorectal cancer (27) or patients with metastatic colorectal cancer (28).
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| Contributor(s) |
Hamm A, Prenen H, Wenes M, Delamarre E, Van Delm W, Schmidt T, Weitz J, Sarmiento R, Dezzi A, Gasparini G, Rothé F, Hendlisz A, D’Hoore A, Iserentant H, Pejcinovski M, Schmitz R, Mazzone M |
| Citation(s) |
25814648 |
| Submission date |
Jun 07, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Rekin's Janky |
| E-mail(s) |
Nucleomics.Bioinformatics@vib.be
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| Organization name |
VIB
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| Department |
Nucleomics Core
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| Street address |
Herestraat 49 Box 816
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| City |
Leuven |
| ZIP/Postal code |
B-3000 |
| Country |
Belgium |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (93)
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| Relations |
| BioProject |
PRJNA207669 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE47756_RAW.tar |
26.2 Mb |
(http)(custom) |
TAR |
| GSE47756_non-normalized.txt.gz |
16.3 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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