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Series GSE4816 Query DataSets for GSE4816
Status Public on May 12, 2006
Title Gene expression profiles of the P1 bladder isolated from SMAA or SMAGA (Acta2 or Actg2) transgenic and wild type mice. (GUDMAP Series ID: 2)
Organism Mus musculus
Experiment type Expression profiling by array
Summary The long term objective is to create an encyclopedia of the expression levels of all genes in multiple components of the developing bladder. The central thesis is straightforward. The combination of laser capture microdissection (LCM) plus microarray analysis offers a powerful, efficient and effective method for the creation of a global gene expression atlas of the developing bladder. Microarrays with essentially complete genome coverage can be used to quantitate expression levels of every gene in laser capture microdissected components of the developing bladder. The ensuing rapid read-out provides an expression atlas that is more sensitive, more economical and more complete than would be possible by in situ hybridizations alone. As a first step we sought to determine if expression of the reporter gene (EGFP or EYFP) used to identify smooth muscle cells altered the gene expression profile of the bladder.
Keywords: Comparison of postnatal day 1 bladders.
Overall design Postnatal day 1 bladders were isolated from transgenic and wild-type mice to determine the effects of transgene expression on the gene expression profile in the bladder.
Contributor(s) Lessard J, Szucsik JC
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Submission date May 12, 2006
Last update date Feb 11, 2019
Contact name GUDMAP Developers
Phone +44 131 651 8500
Organization name IGMM MRC Human Genetics Unit
Lab GUDMAP Database Group
Street address Crewe Road
City Edinburgh
ZIP/Postal code EH4 2XU
Country United Kingdom
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (12)
GSM108528 13B
GSM108529 15B
GSM108530 40B
BioProject PRJNA95621

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Supplementary file Size Download File type/resource
GSE4816_RAW.tar 46.1 Mb (http)(custom) TAR (of CEL)

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