|
| Status |
Public on Mar 13, 2014 |
| Title |
Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia (mRNA) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
The aim of this study was to determine the role that miRNAs have on influencing murine microgial phenotypes under M1(LPS) and M2a (IL-4) stimulating conditions.
This Series includes expression data obtained from mRNA gene expression microarrays; miRNA expression profiles obtained from the same RNA samples were deposited as a separate Series.
|
| |
|
| Overall design |
9 total samples were analyzed, n=3 for the three stimulating conditions (resting state, LPS and IL-4) for murine primary microglia. This allowed us to perform the following pairwise comparisons: PBS vs. LPS, and PBS vs. IL-4. This was performed for both mRNA and miRNA gene expression profiles.
|
| |
|
| Contributor(s) |
Freilich R, Ikezu T |
| Citation(s) |
24244499 |
| Submission date |
Jul 29, 2013 |
| Last update date |
Mar 13, 2014 |
| Contact name |
Tsuneya Ikezu |
| E-mail(s) |
tikezu@bu.edu
|
| Organization name |
Boston University School of Medicine
|
| Department |
BUSM - Department of Pharmacology and Experimental Therapeutics
|
| Lab |
Laboratory of Molecular NeuroTherapeutics
|
| Street address |
72 East Concord St
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11078 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [CDF: MoGene10stv1_Mm_ENTREZG_13] |
|
| Samples (9)
|
| GSM1197448 |
Primary murine microglia - IL-4 Stimulated rep1 |
| GSM1197449 |
Primary murine microglia - IL-4 Stimulated rep2 |
| GSM1197450 |
Primary murine microglia - IL-4 Stimulated rep3 |
| GSM1197451 |
Primary murine microglia - LPS Stimulated rep1 |
| GSM1197452 |
Primary murine microglia - LPS Stimulated rep2 |
| GSM1197453 |
Primary murine microglia - LPS Stimulated rep3 |
| GSM1197454 |
Primary murine microglia - PBS Stimulated rep1 |
| GSM1197455 |
Primary murine microglia - PBS Stimulated rep2 |
| GSM1197456 |
Primary murine microglia - PBS Stimulated rep3 |
|
| This SubSeries is part of SuperSeries: |
| GSE49331 |
Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia |
|
| Relations |
| BioProject |
PRJNA213639 |
Less...
More...