|
| Status |
Public on Nov 06, 2013 |
| Title |
Profiling Methylomic Alterations in Postmortem Prefrontal Cortex Tissues of Individuals with Alcohol Use Disorders |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
Analysis of methylomic alternations related with alcohol use disorders (AUD). The hypothesis is that chronic alcohol consumption might alter genome-wide DNA methylation patterns.
The results suggest that differential DNA methylation might be invovled in neuradaptations to alcohol.
|
| |
|
| Overall design |
Genomic DNA was extraced from postmortem prefrontal cortex tissues of 23 AUD cases and 23 matched controls. Both AUD cases and matched controls are assessed with DSM-IV
|
| |
|
| Contributor(s) |
Zhang H |
| Citation(s) |
24163133, 26763658 |
| Submission date |
Jul 31, 2013 |
| Last update date |
Oct 08, 2019 |
| Contact name |
Huiping Zhang |
| E-mail(s) |
huipingz@bu.edu
|
| Phone |
6173583689
|
| Organization name |
Boston University School of Medicine
|
| Department |
Psychiatry
|
| Street address |
72 East Concord Street
|
| City |
Boston |
| State/province |
Massachusetts |
| ZIP/Postal code |
02118 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA213875 |
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