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| Status |
Public on Aug 01, 2015 |
| Title |
Saturated fatty acids induced genes and ISR target genes in pancreatic beta cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To identify the genes induced by lipotoxicity and integrated stress response in pancreatic beta cells, we have employed whole genome microarray expression in panvreatic beta cell line MIN6m9 cells.
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| Overall design |
First microarray analysis : Wild type MIN6m9 cells were treated with Palmitate, Oleate or negative control condition. Second microarray analysis : Wild type and Fv2E-PERK transgened MIN6m9 cells were treated with mock or artificial dimerizer AP20187(AP) in various time course.
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| Contributor(s) |
Kurahashi K, Mori T, Ogura A, Nomura A, Miyamoto C, Oyadomari M, Miyake M, Matsumoto T, Oyadomari S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Aug 08, 2013 |
| Last update date |
Feb 02, 2018 |
| Contact name |
Seiichi Oyadomari |
| E-mail(s) |
oyadomar@genome.tokushima-u.ac.jp
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| Phone |
81-88-633-9450
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| Organization name |
Institute for Genome Research
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| Department |
Division of Molecular Biology
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| Street address |
3-18-15 Kuramoto
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| City |
Tokushima |
| State/province |
Tokushima |
| ZIP/Postal code |
770-8503 |
| Country |
Japan |
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| Platforms (1) |
| GPL10787 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Probe Name version) |
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| Samples (21)
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| GSM1204339 |
MIN6m9, WT, Ole, rep1 |
| GSM1204340 |
MIN6m9, WT, Ole, rep2 |
| GSM1204341 |
MIN6m9, WT, Ole, rep3 |
| GSM1204342 |
MIN6m9, WT, Pal, rep1 |
| GSM1204343 |
MIN6m9, WT, Pal, rep2 |
| GSM1204344 |
MIN6m9, WT, Pal, rep3 |
| GSM1204345 |
MIN6m9, WT, Mock, rep1 |
| GSM1204346 |
MIN6m9, WT, Mock, rep2 |
| GSM1204347 |
MIN6m9, Fv2E PERK, Mock, rep1 |
| GSM1204348 |
MIN6m9, Fv2E PERK, Mock, rep2 |
| GSM1204349 |
MIN6m9, Fv2E PERK, AP 6h, rep1 |
| GSM1204350 |
MIN6m9, Fv2E PERK, AP 6h, rep2 |
| GSM1204351 |
MIN6m9, Fv2E PERK, AP 12h, rep1 |
| GSM1204352 |
MIN6m9, Fv2E PERK, AP 12h, rep2 |
| GSM1204353 |
MIN6m9, Fv2E PERK, AP 24h, rep1 |
| GSM1204354 |
MIN6m9, Fv2E PERK, AP 24h, rep2 |
| GSM1204355 |
MIN6m9, Fv2E PERK, AP 48h, rep1 |
| GSM1204356 |
MIN6m9, Fv2E PERK, AP 48h, rep2 |
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| Relations |
| BioProject |
PRJNA214595 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE49647_RAW.tar |
66.9 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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