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Series GSE49705 Query DataSets for GSE49705
Status Public on Jul 15, 2015
Title Transcriptome analysis of Prdm11 knockout mice after OVA challenge
Organism Mus musculus
Experiment type Expression profiling by array
Summary PRDM family members encode for progeins functionally associated with the control of cell proliferation, differentiation as well as apoptosis action in cell and tissue-specific menner. As important factors in maintenance and differentiation of human and mouse ES cells several PRDM family members were identified. Prdm11 has and outsider position within the PRDM family due to the lack of zinc-finger domains. However, a zic-finger binding motive i present and likely assue the function of protein-protein interactionl. Prdm11 was described as a candidate for tumor suppresser. However, the function of this gene is still unknown. Our study give evidence a new functional association of Prdm11 in allergic disease and asthma.
Overall design Total RNA obtained from 1/2 lung of 4 female mice of each analysed group (widltype, wildtype challenged, mutant, mutant challenged)
Contributor(s) Beckers J, Horsch M
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Submission date Aug 09, 2013
Last update date Jun 14, 2018
Contact name Martin Irmler
Organization name Helmholtz Zentrum M√ľnchen GmbH
Department Institute of Experimental Genetics
Lab Gene Regulation & Epigenetics
Street address Ingolstaedter Landstrasse 1
City Neuherberg
State/province Bayern
ZIP/Postal code 85764
Country Germany
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (16)
GSM1205178 lung wt_rep1
GSM1205179 lung wt_rep2
GSM1205180 lung wt_rep3
BioProject PRJNA215095

Download family Format
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Supplementary file Size Download File type/resource
GSE49705_RAW.tar 3.1 Mb (http)(custom) TAR
Raw data not provided for this record
Processed data included within Sample table

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