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Series GSE50183 Query DataSets for GSE50183
Status Public on Aug 27, 2013
Title Effect of adiponectin deficiency on pulmonary responses to subacute ozone exposure in mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Adiponectin is an adipose-derived hormone with anti-inflammatory activity. Following subacute ozone exposure (0.3 ppm for 24-72 h), pulmonary neutrophilic inflammation is augmented in adiponectin deficient mice. The purpose of this study was to use microarrays to examine the impact of adiponectin deficiency on changes in pulmonary gene expression induced by ozone, a common air pollutant.
 
Overall design Lungs were harvested from wildtype and mice that were genetically deficient in adiponectin. Mice were exposed either to room air or to ozone (0.3 ppm) for 72 h. RNA was extracted and microarray analysis of gene expression performed. Both male and female mice were used.
 
Contributor(s) Shore SA, Kasahara DI
Citation(s) 24381131
Submission date Aug 26, 2013
Last update date May 04, 2018
Contact name Stephanie A Shore
E-mail(s) sshore@hsph.harvard.edu
Organization name Harvard School of Public Health
Department Environmental Health
Lab Shore Lab
Street address 665 Huntigton Av Bld1 room 307
City Boston
State/province MA
ZIP/Postal code 02115
Country USA
 
Platforms (1)
GPL8321 [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
Samples (16)
GSM1215202 whole lung RNA, wildtype mouse, air exposed, male replicate 1
GSM1215203 whole lung RNA, wildtype mouse, air exposed, male replicate 2
GSM1215204 whole lung RNA, wildtype mouse, air exposed, female replicate 1
Relations
BioProject PRJNA216989

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE50183_RAW.tar 33.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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