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| Status |
Public on Dec 01, 2014 |
| Title |
HMLEN cells with Vector Control vs SNAIL vs SNAIL/FBXO11 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of mouse HMLEN breast cancer cells (HMLE cells transformed with -Neu oncogene) stably tranduced with pLEX-MCS based lentivirus. Three groups were compared, Vector cells, SNAIL expressing cells; and SNAIL+FBXO11 expressing cells. SNAIL expression induced strong EMT phenotype while SNAIL/FBXO11 reversed cells back to epithelial cells.
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| |
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| Overall design |
Three-condition experiments Vector vs SNAIL vs SNAIL/FBXO11. Two replicates per each condition.
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| |
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| Contributor(s) |
Zheng H, Wei Y |
| Citation(s) |
25203322 |
| Submission date |
Sep 16, 2013 |
| Last update date |
Feb 29, 2024 |
| Contact name |
Yong Wei |
| E-mail(s) |
yongwei@princeton.edu
|
| Organization name |
Princeton University
|
| Department |
Molecular Biology
|
| Lab |
Kang
|
| Street address |
LTL227 Wathington Road
|
| City |
Plainsboro |
| State/province |
NJ |
| ZIP/Postal code |
08536 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17077 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE50889 |
Vector Control vs SNAIL vs SNAIL/FBXO11 |
|
| Relations |
| BioProject |
PRJNA219304 |
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