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Series GSE51013 Query DataSets for GSE51013
Status Public on Feb 18, 2016
Title Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways
Organism Danio rerio
Experiment type Expression profiling by array
Summary The mammalian heart has poor regenerative capacity following injury. In contrast, certain lower vertebrates such as zebrafish retain a robust capacity for regeneration into adult life. Here we use an integrated approach to identify evolutionary conserved regenerative miRNA-dependant regulatory circuits in the heart. We identified novel miRNA-dependant networks involved in critical biological pathways, which are differentially utilized between the infarcted mouse heart and the regenerating zebrafish heart.
 
Overall design 2 conditions, 4 biological replicates per condition
 
Contributor(s) Crippa S, Ounzain S, Ibberson M, Nemir M, Berthonneche C, Sarre A, Boisset G, Harshman K, Xenarios I, Diviani D, Schorderet D, Pedrazzini T
Citation(s) 26857418
Submission date Sep 19, 2013
Last update date Jan 25, 2018
Contact name Mark Ibberson
Organization name SIB Swiss Institute of Bioinformatics
Department Vital-IT
Street address Genopode building
City Lausanne
ZIP/Postal code CH-1015
Country Switzerland
 
Platforms (1)
GPL1319 [Zebrafish] Affymetrix Zebrafish Genome Array
Samples (8)
GSM1234847 Heart, Control, rep1
GSM1234848 Heart, Control, rep2
GSM1234849 Heart, Control, rep3
This SubSeries is part of SuperSeries:
GSE51014 Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways
Relations
BioProject PRJNA219633

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE51013_RAW.tar 14.9 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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