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| Status |
Public on Apr 28, 2014 |
| Title |
Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating precision medicine (PMed) trials |
| Platform organism |
Canis lupus familiaris |
| Sample organism |
Canis lupus |
| Experiment type |
Expression profiling by array
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| Summary |
Feasibility trial to examine the ability to conduct molecular guided therapy in a geographically distributed systems within strict time constraints
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| Overall design |
Canine patients were enrolled across a broad panel of tumor types where tumor samples were acquired and processed to preserve RNA quality for genomic analysis at distributed locations to predict possible effective therapies. Genomic driven therapy suggestion derived using a collection of algorithms based on tumor expression levels.
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| Contributor(s) |
Paoloni M, Webb C, Mazcko C, Cherba D, Lana S, Ehrhart E, Charles B, Lana S, Fehling H, Kumar L, Vail D, Henson M, Childress M, Kitchell B, Kingsley C, Kim S, Neff M, Davis B, Khanna1 C, Trent J |
| Citation(s) |
24637659 |
| Submission date |
Sep 24, 2013 |
| Last update date |
Apr 28, 2014 |
| Contact name |
David Cherba |
| E-mail(s) |
david.cherba@vai.org
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| Phone |
616 234 5382
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| Organization name |
Van Andel Institute
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| Department |
Bioinformatics and Biostatistic Core
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| Street address |
333 Bostwick Ave
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| City |
Grand Rapids |
| State/province |
MI |
| ZIP/Postal code |
49503 |
| Country |
USA |
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| Platforms (1) |
| GPL3738 |
[Canine_2] Affymetrix Canine Genome 2.0 Array |
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| Samples (23)
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| Relations |
| BioProject |
PRJNA221340 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE51131_RAW.tar |
52.7 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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