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| Status |
Public on Jun 21, 2007 |
| Title |
Wilms' tumor 1 WT1(-KTS) isoform time course induction in U2OS cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The Wilms' tumor suppressor gene (WT1) encodes a zinc finger transcription factor that plays important roles during development of several organs including metanephric kidneys. A number of WT1 target genes have been identified, but the detailed mechanisms by which WT1 orchestrates renal development remain elusive. To identify WT1 target genes relevant to development, genome-wide expression profiling was performed using oligonucleotide microarrays representing 39,000 human transcripts
Keywords: Wilms' tumor 1 (WT1) gene, -KTS isoform; time course
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| Overall design |
Sample_source_name: UB27 cells, U2OS cells with Tetracycline-repressible WT1(-KTS) expression
Sample_characteristics: U2OS cell line (osteosarcoma; female), Tetracycline-repressible WT1(-KTS) expression, time-course induction
of WT1(-KTS) expression
Sample_description: WT1(-KTS) expression was induced for 4, 8 or 12
hrs and the expression profile of each time-points was compared to the
uninduced sample (0 hr).
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| |
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| Contributor(s) |
KIM H, Kim M, Cam M, Malik K, Lee S |
| Citation(s) |
17430890 |
| Submission date |
Jun 21, 2006 |
| Last update date |
Aug 10, 2018 |
| Contact name |
WeiPing Chen |
| E-mail(s) |
weipingChen@niddk.nih.gov
|
| Phone |
301-496-0175
|
| Organization name |
NIDDK/NIH
|
| Department |
GCL
|
| Lab |
Genomics Core Lab
|
| Street address |
Bldg 8, Room 1A11, NIDDK/NIH
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
|
| Samples (4)
|
| GSM115522 |
WT1(-KTS) expression induced for 12 hrs 01-14-03_Lee_U133A_12_2 |
| GSM115523 |
WT1(-KTS) expression induced for 4 hrs 01-14-03_Lee_U133A_4_2 |
| GSM115524 |
WT1(-KTS) expression induced for 8 hrs 01-14-03_Lee_U133A_8_2 |
| GSM115525 |
Uninduced control 01-14-03_Lee_U133A_Tet |
|
| Relations |
| BioProject |
PRJNA96611 |
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