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| Status |
Public on Oct 30, 2013 |
| Title |
Intra-MZ pair discordance and longitudinal variation of whole-genome scale DNA methylation in adults |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
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| Summary |
In this study, we used Illumina Infinium HumanMethylation450 Beadchips to compare DNA methylation profiles in blood from 10 pairs of MZ twins and 8 individuals recruited at 0, 3, 6, and 9 months.
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| Overall design |
MZ Group (Group A) contained 10 pairs of MZ twins ranging from 23 to 74 years old, including 8 female and 12 male subjects.Longitudinal study group (Group B) included a pair of MZ (male) twins and 6 unrelated individuals (3 male, 3 female), aged from 24 to 39. Except subject H, all participants in Longitudinal study group (Group B) were recalled every 3 months for 9 months (0, 3, 6, and 9 m). Subject H was studied only at 0, 6, and 9 months. Bisulphite converted DNA from the 60 samples were hybridised to the Illumina Infinium 450k Human Methylation Beadchip
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| Contributor(s) |
Zhang N, Zhao S, Zhang S, Chen J, Lu D, Shen M, Li C |
| Citation(s) |
26248206 |
| Submission date |
Oct 17, 2013 |
| Last update date |
Apr 07, 2020 |
| Contact name |
Na Zhang |
| E-mail(s) |
zngoluk@hotmail.com
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| Organization name |
Institute of Forensic Science, Ministry of Justice
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| Street address |
1347 West Guangfu Rd.
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| City |
Shanghai |
| ZIP/Postal code |
200063 |
| Country |
China |
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| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (60)
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| Relations |
| BioProject |
PRJNA222982 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE51388_Group_A_unmethylated_methylated.txt.gz |
42.3 Mb |
(ftp)(http) |
TXT |
| GSE51388_Group_B_unmethylated_methylated.txt.gz |
63.7 Mb |
(ftp)(http) |
TXT |
| GSE51388_RAW.tar |
183.1 Mb |
(http)(custom) |
TAR |
| Processed data included within Sample table |
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