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| Status |
Public on Oct 30, 2013 |
| Title |
Gene expression data for liver, adipose, and skeletal muscle tissues of MKR and Healthy mice. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
MKR mice is a Type 2 Diabetic mice, which was created by expressing mutation in IGF1 receptor in the skeletal muscle, and is widely used in diabetes research. Gene expression differences between MKR mice and Healthy (Wild type) mice are poorly understood.
We used microarrays to detail the differences between gene expression in liver, fat, and skeletal muscle of MKR and Healthy mice.
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| Overall design |
Male 10-weeks old FVB/N – MKR and wild type mice were used for the microarray studies. 3 biological replicates for each tissue type and for both MKR and WT mice were used in the studies.
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| Contributor(s) |
Kumar A, Keembiyehetty C, Shiloach J, Betenbaugh MJ, Gallagher EJ, LeRoith D |
| Citation(s) |
25029527 |
| Submission date |
Oct 29, 2013 |
| Last update date |
Jul 18, 2014 |
| Contact name |
Amit Kumar |
| E-mail(s) |
amit.kumar3@nih.gov
|
| Phone |
443-850-6787
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| Organization name |
National Institutes of Health
|
| Department |
NIDDK
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| Lab |
NIDDK Biotechnology Core Lab
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| Street address |
14A Service Rd West., Room 176
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20814 |
| Country |
USA |
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| Platforms (1) |
| GPL10740 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [probe set (exon) version] |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA225626 |
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