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Series GSE51944 Query DataSets for GSE51944
Status Public on Nov 01, 2013
Title Robust Differentiation of Islet Progenitors into Functional Insulin-secreting Cells by Suppression of Key Transcription Regulators
Organism Mus musculus
Experiment type Expression profiling by array
Summary Gene profiling revealed that differentiation was accompanied by suppression of a range of transcription regulator genes typical of islet progenitor cells. In order to understand molecular mechanisms of differentiation, transcriptome-wide gene expression analysis was performed on purified islet progenitors at days 0, 1 and 4 of differentiation together with adult islets as a control.
 
Overall design In order to understand molecular mechanisms of differentiation, transcriptome-wide gene expression analysis was performed on purified islet progenitors at days 0, 1 and 4 of differentiation together with adult islets as a control.
 
Contributor(s) Jiang FX, Nguyen Q, Mehta M, Morahan G
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Oct 31, 2013
Last update date Jun 14, 2018
Contact name Munish Mehta
E-mail(s) munish.mehta@uwa.edu.au
Phone +61-8-92240397
Organization name Harry Perkin Institute of Medical Reasearch
Department Diabetes Research Unit
Lab DRF
Street address L6, Rear 50 Murray Street
City Perth
State/province WA
ZIP/Postal code 6000
Country Australia
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (13)
GSM1255606 Embroynic Stem Cells, Replicate 1
GSM1255607 Embroynic Stem Cells, Replicate 2
GSM1255608 Islet Progenitors at Day 0 of differentiation, Replicate 1
Relations
BioProject PRJNA225884

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE51944_RAW.tar 3.1 Mb (http)(custom) TAR
GSE51944_non-normalized.txt.gz 2.1 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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