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| Status |
Public on Jan 19, 2014 |
| Title |
Overexpression of splicing factor SRSF6 in mouse skin |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Many biological processes involve post-transcriptional regulation of gene expression by alternative pre-mRNA splicing. Here, we show that an alternative splicing factor SRSF6 affects tissue homeostasis of the skin.
In this dataset, we study effects on gene expression and alternative splicing upon SRSF6 overexpression (+doxycycline) in mouse skin using inducible R26-rtTA+/-, ColA1-TREtight-SRSF6+/- transgenic mice
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| Overall design |
4 mixed-background strain samples (2 SRSF6-induced skin samples and 2 uninduced skin control samples)
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| Contributor(s) |
Jensen MA, Krainer AR |
| Citation(s) |
24440982 |
| Submission date |
Nov 18, 2013 |
| Last update date |
Jun 08, 2015 |
| Contact name |
Mads A Jensen |
| Organization name |
Cold Spring Harbor Laboratory
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| Street address |
1 Bungtown Road
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| City |
Cold Spring Harbor |
| State/province |
New York |
| ZIP/Postal code |
11724 |
| Country |
USA |
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| Platforms (2) |
| GPL10740 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [probe set (exon) version] |
| GPL17984 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version, ENSG 60] |
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| Samples (8)
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| GSM1267211 |
skin_control, biological rep1 (exon-level) |
| GSM1267212 |
skin_control, biological rep2 (exon-level) |
| GSM1267213 |
skin_SRSF6, biological rep1 (exon-level) |
| GSM1267214 |
skin_SRSF6, biological rep2 (exon-level) |
| GSM1274320 |
skin_control, biological rep1 (gene-level) |
| GSM1274321 |
skin_control, biological rep2 (gene-level) |
| GSM1274322 |
skin_SRSF6, biological rep1 (gene-level) |
| GSM1274323 |
skin_SRSF6, biological rep2 (gene-level) |
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| Relations |
| BioProject |
PRJNA229844 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE52458_AKMJ013111_1A-2-new+D21.CEL.gz |
4.4 Mb |
(ftp)(http) |
CEL |
| GSE52458_AKMJ052410_Y1+SK_D21.CEL.gz |
4.8 Mb |
(ftp)(http) |
CEL |
| GSE52458_AKMJ052410_Y1-SK_D21.CEL.gz |
4.8 Mb |
(ftp)(http) |
CEL |
| GSE52458_AKMJ101510_1A-3_litt+d21.CEL.gz |
4.2 Mb |
(ftp)(http) |
CEL |
| Processed data included within Sample table |
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