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Status |
Public on Nov 03, 2014 |
Title |
the whole-genome methylation profile of esophageal squamous cell carcinoma |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by array
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Summary |
Both genetic and epigenetic aberrations are linked by intricate crosstalk, and can either individually or in synergy lead to the development of cancer. Accumulating evidence suggests that epigenetic changes such as alterations in DNA methylation play a crucial role in ESCC. We performed a Illumina Infinium HumanMethylation450 BeadChip to examine the global methylation signature of esophageal squamous cell carcinoma of Chinese patients.
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Overall design |
DNA methylation profiles of esophageal squamous cell carcinoma (4 samples), paired adjacent normal surrounding tissues (4 samples) and normal esophagus mucosa from healthy individuals (4 samples) were generated using Infinium methylation 450K BeadChips from Illumina (Illumina, San Diego, USA).
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Contributor(s) |
Li XF, Jiang CY, Zhang JR, Zheng YF |
Citation(s) |
25050929 |
Submission date |
Nov 29, 2013 |
Last update date |
Mar 22, 2019 |
Contact name |
xufeng li |
E-mail(s) |
lixufeng1984@hotmail.com
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Phone |
+8615018731689
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Organization name |
Southern Medical University
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Department |
oncology center of zhujiang hospital
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Street address |
gongye avenue 253
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City |
guangzhou |
State/province |
guangdong |
ZIP/Postal code |
510282 |
Country |
China |
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Platforms (1) |
GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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Samples (12)
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Relations |
BioProject |
PRJNA230249 |