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Series GSE53086 Query DataSets for GSE53086
Status Public on Dec 31, 2016
Title Effects of rapamycin exposure on zebrafish ZF4 cells
Organism Danio rerio
Experiment type Expression profiling by array
Summary mTOR inhibitor rapamycin is a well-known anticancer and immunosuppressant agent. Effects of rapamycin on zebrafish cells have not been previously studied using transcriptome analyses.
Our microarray analysis on ZF4 cells showed that rapamycin treatment modulated a large set of genes with varying functions including protein synthesis, assembly of mitochondrial and proteosomal machinery, cell cycle, metabolism, and oxidative phosphorylation.
 
Overall design Zebrafish ZF4 cells exposed to 100nM rapamycin was profiled using Zebrafish Affymetrix Gene Chips. Normalization by RMA and class comparison analyses were performed using BRB Array Tools.
 
Contributor(s) Konu O, Sucularli C
Citation(s) 27035657
Submission date Dec 06, 2013
Last update date Jan 25, 2018
Contact name Ozlen Konu
E-mail(s) konu@fen.bilkent.edu.tr
Organization name Bilkent University
Department Molecular Biology and Genetics
Street address Bilkent University
City Ankara
ZIP/Postal code 06800
Country Turkey
 
Platforms (1)
GPL1319 [Zebrafish] Affymetrix Zebrafish Genome Array
Samples (5)
GSM1282121 rap_replicate1
GSM1282122 dmso_replicate1
GSM1282123 rap_replicate2
Relations
BioProject PRJNA230818

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE53086_RAW.tar 10.0 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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