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Series GSE54086 Query DataSets for GSE54086
Status Public on Jan 16, 2014
Title Microarray analysis of Nurr1 and Foxa2 synergisitic effect for DA neuron induction
Organism Mus musculus
Experiment type Expression profiling by array
Summary Analysis of dopaminergic neuronal gene expression changes by Nurr1 and/or Foxa2 overexpression. Result provides that Foxa2 potentiates Nurr1-induced DA neuronal phenotype gene expression.
 
Overall design To identify the syergism of Nurr1 and Foxa2 for developing DA neural precursors, neural precusor cells (NPCs) isolated from embryonic brain were treated control, Nurr1, Foxa2 and Nurr1-Foxa2 retrovirus. After treatment of retroviruses, NPCs were cultrued in N2 media withdrawn mitogen (bFGF, EGF) for differetiation of DA neuron. Total RNA was obtained from NPCs in differentiation day 2.
 
Contributor(s) Yi S, He X, Lee S
Citation(s) 24496614
Submission date Jan 15, 2014
Last update date Jun 14, 2018
Contact name Sang-Hun Lee
E-mail(s) leesh@hanyang.ac.kr
Phone 82-2-2220-0625
Organization name College of medicine, Hanyang University
Department biochemistry and molecular biology
Street address 222 Wangsimni-ro, Seongdong-gu
City Seoul
ZIP/Postal code 133-791
Country South Korea
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (4)
GSM1307469 Control_NPCs_rep1
GSM1307470 Nurr1_NPCs_rep1
GSM1307471 Foxa2_NPCs_rep1
Relations
BioProject PRJNA235158

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE54086_RAW.tar 3.1 Mb (http)(custom) TAR
GSE54086_non-normalized.txt.gz 749.6 Kb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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