|
| Status |
Public on Mar 06, 2014 |
| Title |
Genome wide localization of chromatin bound NUP98-PHF23 (NP23) |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We analyzed the genome wide localization of H3K4me3, H3K27me3 and the NUP98-PHF23 (with V5 tag) fusion protein which binds H3K4me3 via its PHD finger, using ChIP-seq. Results correlated with gene expression profiles. NUP98-PHF23 bound only 1.6% of H3K4me3 marks including Hoxa/b + Meis1.
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| |
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| Overall design |
Assess H3K4me3 and H3K27me3 histone marks, and correlate these marks with chromatin binding of the NP23 fusion protein using lymphoblast and myeloblast cell lines derived from NP23 leukemias.
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| |
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| Contributor(s) |
Gough SM, Yang F, Walker RL, Zhu Y, Pineda M, Bilke S, Meltzer PS, Aplan PD |
| Citation(s) |
24535671 |
| Submission date |
Feb 07, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Yuelin Jack Zhu |
| E-mail(s) |
zhujack@mail.nih.gov
|
| Phone |
(240)760-7439
|
| Organization name |
NCI
|
| Department |
Genetics Branch, Center for Cancer Research
|
| Lab |
Dr. Paul Meltzer's Lab
|
| Street address |
9000 Rockville Pike
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
|
| Samples (13)
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA237651 |
| SRA |
SRP036859 |
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