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Series GSE54787 Query DataSets for GSE54787
Status Public on Mar 06, 2014
Title Gene expression study of leukemic and premalignant hematopoietic tissues from NUP98-PHF23 (NP23) mice.
Organism Mus musculus
Experiment type Expression profiling by array
Summary NUP98-PHF23 is oncogenic and results in a Hoxa/b + Meis1 overexpression in NP23 leukemias and in premalignant (clinically healthy) hematopoietic tissues.
 
Overall design Gene expression profiles from AML, pre-T LBL and B-ALL were compared to wild type bone marrow, thymus and spleen tissues respectively. Similarly, gene expression profiles from premalignant (clinically healthy) NP23 bone marrow, thymus and spleen were compared to wild type bone marrow, thymus and spleen tissues respectively. 106A and 748T lymphoblastic cell lines were compared to wild type thymic tissue.
 
Contributor(s) Gough SM, Lee F, Walker RL, Pineda M, Zhu Y, Bilke S, Meltzer PS, Aplan PD
Citation(s) 24535671
Submission date Feb 07, 2014
Last update date Jun 14, 2018
Contact name Yuelin Jack Zhu
E-mail(s) zhujack@mail.nih.gov
Phone (240)760-7439
Organization name NCI
Department Genetics Branch, Center for Cancer Research
Lab Dr. Paul Meltzer's Lab
Street address 9000 Rockville Pike
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (48)
GSM1323996 879BM AML
GSM1323997 841SPL Tg
GSM1323998 835BM WT
This SubSeries is part of SuperSeries:
GSE54788 NUP98-PHF23
Relations
BioProject PRJNA237650

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE54787_RAW.tar 3.1 Mb (http)(custom) TAR
GSE54787_non-normalized.txt.gz 19.2 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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