|
| Status |
Public on Feb 20, 2014 |
| Title |
UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
This report not only adds a novel mechanism to the current dogma on achieving global shortening of 3'UTRs, but also unveils a novel function of the NMD pathway in establishing tissue-specific transcriptome identity
|
| |
|
| Overall design |
We first generated prospermatogonia-specific Upf2 conditional knockout mice (Ddx4-Cre; Upf2 fl/Δ, hereafter called Ddx4-KO) by crossing Ddx4-Cre13 with Upf2 floxed.
|
| |
|
| Contributor(s) |
Yan W, Bo P |
| Citation(s) |
27149259 |
| Submission date |
Feb 19, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Chong Tang |
| E-mail(s) |
leochong718@gmail.com
|
| Phone |
7753389788
|
| Organization name |
University of Nevada Reno
|
| Department |
physiology
|
| Lab |
wei yan
|
| Street address |
1664 N.Virginia Street MS330
|
| City |
Reno |
| State/province |
Nevada |
| ZIP/Postal code |
89557 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9185 |
Illumina Genome Analyzer (Mus musculus) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA238821 |
| SRA |
SRP038144 |
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