|
| Status |
Public on Sep 01, 2014 |
| Title |
Hepatocyte ductal metaplasia in chronic mouse liver injury |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Expression profiling of hepatocytes-derived ductal cells with properties intermediate between mature hepatocytes and cholangiocytes
|
| |
|
| Overall design |
Chimeric adult mice were generated where mature hepatocytes were marked with a fluorescent red marker. Chronic injury was induced for ~6weeks and three cell types were isolated by FACS (Influx, BD) for expression analysis by RNAseq based on cell surface phenotype and origin: hepatocytes (n=3), hepatocyte-derived oval cells (1c3+, n=5), and cholangiocyte-derived oval cells (1c3+, n=5).
|
| |
|
| Contributor(s) |
Tarlow BD, Grompe M |
| Citation(s) |
25312494 |
| Submission date |
Mar 04, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Branden Tarlow |
| E-mail(s) |
btarlow@gmail.com
|
| Phone |
(503) 494-6889
|
| Organization name |
Oregon Health & Science University
|
| Department |
Pediatrics
|
| Lab |
Markus Grompe, MD
|
| Street address |
3181 SW Sam Jackson Park Road
|
| City |
Portland |
| State/province |
OR |
| ZIP/Postal code |
97239 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (14)
|
|
| Relations |
| BioProject |
PRJNA239955 |
| SRA |
SRP039386 |
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