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Series GSE55694 Query DataSets for GSE55694
Status Public on Jul 01, 2014
Title Murine study of combined LPS and modified immunoglobulins associated gene expression changes in vivo
Organism Mus musculus
Experiment type Expression profiling by array
Summary We systematically assessed the transcriptomic changes of lipopolysaccharides (LPS) of mice upon stimulation with immunoglobulins (IVIg), modified immunoglobulins (modIVIg) or vehicle controls in kidney, blood and liver in vivo.
Data indicate different in vivo responses to LPS in conjunction with IVIg, modIVIg or vehicle.
 
Overall design RNA from murine liver and kidney tissues (LPS+vehicle, LPS+IVIg, LPS+modIVIg; four samples each group) as well as circulating leukocytes from WBC (three samples each group) was extracted and subject to microarray analysis for comparison of transcriptomic responses. Normalization and quality control was performed for each organ separately.
 
Contributor(s) Lindig S, Bauer M, Vassilev TL
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Mar 07, 2014
Last update date Jun 14, 2018
Contact name S. Lambeck
Organization name JUH
Street address Erlanger Allee 101
City Jena
ZIP/Postal code 07743
Country Germany
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (31)
GSM1341817 Liver_LPS+vehicle_rep.1
GSM1341818 Liver_LPS+vehicle_rep.2
GSM1341819 Liver_LPS+vehicle_rep.3
Relations
BioProject PRJNA240567

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE55694_RAW.tar 3.1 Mb (http)(custom) TAR
GSE55694_non-normalized.txt.gz 3.2 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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