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Series GSE56352 Query DataSets for GSE56352
Status Public on Mar 31, 2014
Title Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer
Organism Homo sapiens
Experiment type Expression profiling by array
Summary We analyzed transcriptional changes in 4 prostate cancer cell lines following treatment with the BET inhibitor I-BET762 using Affymetrix Human Genome U133 Plus 2.0 Arrays.
 
Overall design Four prostate cancer cell lines (NCI-H660, VCaP, LNCaP, PC-3) were treated with DMSO (control) or I-BET762 at 0.5uM or 10uM concentrations for 24 hours. Two biological replicates are included for each treatment group.
 
Contributor(s) Wyce A, Degenhardt Y, Bai Y, Le B, Korenchuk S, Crouthamel M, McHugh CF, Vessella R, Creasy CL, Tummino PJ, Barbash O
Citation(s) 24293458
Submission date Mar 31, 2014
Last update date Mar 25, 2019
Contact name Yuchen Bai
E-mail(s) yuchen.v.bai@gsk.com
Phone 610-917-4981
Organization name GlaxoSmithKline
Street address 1250 S Collegeville Road
City Collegeville
State/province PA
ZIP/Postal code 19426
Country USA
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (24)
GSM1359760 NCIH660 DMSO vehicle at 24 hrs, Biological rep1
GSM1359761 NCIH660 DMSO vehicle at 24 hrs, Biological rep2
GSM1359762 NCIH660 GSK525762A .5uM at 24 hrs, Biological rep1
Relations
BioProject PRJNA243023

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56352_RAW.tar 120.5 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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