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Series GSE56493 Query DataSets for GSE56493
Status Public on Nov 03, 2014
Title Expression data from fine-needle aspiration biopsies of breast cancer metastases from different anatomical sites
Organism Homo sapiens
Experiment type Expression profiling by array
Summary To determine whether breast cancer molecular subtypes and tumor characteristics with demonstrated significance in a primary tumor setting can also confer clinically relevant information in breast cancer metastases.
We assessed previously published gene expression modules of seven biological processes and the intrinsic subtypes (PAM50). The translational aspect of the Swedish randomized TEX trial included 112 patients with at least one biopsy from morphologically confirmed loco-regional or distant breast cancer metastasis diagnosed from December 2002 until June 2007. All patients had detailed clinical information, complete follow-up and metastasis gene expression information (Affymetrix array GPL10379).
 
Overall design We performed global gene expression profiling on fine-needle aspirates of metastatic lesions from different anatomical sites obtained from breast cancer patients treated within the Swedish randomized trial (TEX) of first-line chemotherapy for locally advanced or metastatic breast cancer. Samples were collected before commencement of treatment.
 
Contributor(s) Tobin NP, Lindstrom L
Citation(s) 25361981, 29433456, 28972041, 29370583
Submission date Apr 03, 2014
Last update date Jul 31, 2019
Contact name Nicholas Tobin
E-mail(s) tobin.nick@gmail.com
Phone +46 761966368
Organization name Karolinska Institutet
Street address Cancer Center Karolinska
City Stockholm
State/province N/A
ZIP/Postal code 17176
Country Sweden
 
Platforms (1)
GPL10379 Rosetta/Merck Human RSTA Custom Affymetrix 2.0 microarray [HuRSTA-2a520709]
Samples (120)
GSM1362516 1_52070900803933090410408220339034
GSM1362517 2_52070900803933090410408220339035
GSM1362518 3_52070900803933090410408220339036
Relations
BioProject PRJNA244742

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56493_RAW.tar 610.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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