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Series GSE56584 Query DataSets for GSE56584
Status Public on Jul 01, 2014
Title Gene expression profiles of neonatal cardiomyocytes and immortalized heart muscle cells exposed to inflammatory stimuli
Organism Mus musculus
Experiment type Expression profiling by array
Summary We used a transcriptomic approach to systematically compare the response to inflammatory stimuli for two murine cardiomyocyte models.
Our results indicate that murine neonatal cardiomyocytes (NNC) are able to exhibit a pronounced response upon inflammatory stimuli, while HL-1 cells were predominantly recruiting transcripts corresponding to Jak-Stat-signalling.
 
Overall design RNA from murine HL-1 cardiomyocytes and isolated neonatal cardiomyocytes (NNC) stimulated by infectious (PCI) serum or LPS or a cytokine mix (CM) were extracted (n=4 each group) and subjected to microarray analysis for comparison of transcriptomic responses.
 
Contributor(s) Lindig S, Stehr SN
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Apr 08, 2014
Last update date Jun 14, 2018
Contact name S. Lambeck
Organization name JUH
Street address Erlanger Allee 101
City Jena
ZIP/Postal code 07743
Country Germany
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (39)
GSM1364704 NNC_CON_6h_rep.1
GSM1364705 NNC_PCI_6h_rep.1
GSM1364706 NNC_CM_6h_rep.1
Relations
BioProject PRJNA244001

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56584_RAW.tar 3.1 Mb (http)(custom) TAR
GSE56584_non-normalized.txt.gz 3.9 Mb (ftp)(http) TXT
Processed data included within Sample table
Raw data are available on Series record

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