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Series GSE56666 Query DataSets for GSE56666
Status Public on Apr 10, 2014
Title Genetic Diversity Influences the Response of the Brain to Developmental Lead Exposure.
Organism Rattus norvegicus
Experiment type Expression profiling by array
Summary In this study we analyzed the effects of lead-exposure up hippocampal gene expression in males and females exposed to 0ppm, 250ppm and 750ppm lead during two different developmental periods, perinatal (in utero through to weaning at PND21) and postnatal (PND0-PND45), across three strains (Fischer, Long Evans and Sprague Dawley). All tissue was taken at PND 55. We used affymetrix Rat Gene 1.0ST arrays to obtain global gene expression data from each animal, with a group size of 4 for all conditions (Total number of Arrays = 119)
 
Overall design Gene expression was profiled in the hippocampus of rats at no lead exposure (0ppm), 250ppm and 750 ppm lead exposure levels during perinatal and postnatal developmental periods of both males and females of three strains of rat (Fischer, Long Evans and Sprague Dawley).
 
Contributor(s) Schneider J, Anderson D, Talsania K
Citation(s) 24913800
Submission date Apr 09, 2014
Last update date Jan 28, 2020
Contact name David William Anderson
E-mail(s) David.Anderson@jefferson.edu
Phone 2155038827
Organization name Thomas Jefferson University
Department Pathology, Anatomy & Cell Biology
Lab JAH 568
Street address 1020 Locust Street
City Philadelphia
State/province PA
ZIP/Postal code 19107
Country USA
 
Platforms (1)
GPL6247 [RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version]
Samples (119)
GSM1366522 Fischer Control Male Hippocampus 3219
GSM1366523 Fischer Control Male Hippocampus 3220
GSM1366524 Fischer Control Male Hippocampus 3221
Relations
BioProject PRJNA244259

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Supplementary file Size Download File type/resource
GSE56666_RAW.tar 508.5 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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