|
| Status |
Public on Jul 24, 2014 |
| Title |
Regulatory consequences of TARBP2 over-expression in MDA-231 cell-line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Transient transfection of TARBP2 expression vectors (along with GFP controls) followed by transcriptomic profiling revealed that over-expression of TARBP2 resulted in a significant enrichment of sRSE-carrying transcripts among the down-regulated transcripts.
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| |
|
| Overall design |
Transient transfection of CMV-driven TARBP2 was used to over-express this protein in MDA-231 cells. The cells were then subjected to transcripome profiling in comparison to mock-transfected cells.
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| |
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| Contributor(s) |
Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF |
| Citation(s) |
25043050 |
| Submission date |
Apr 21, 2014 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Hani Goodarzi |
| Organization name |
UCSF
|
| Department |
Biochemistry and Biophysics
|
| Street address |
600 16th St, GH S312D
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94158 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (4)
|
| GSM1372079 |
TARBP2 over-expression (pCMV-TARBP2-1)_MDA-231 |
| GSM1372080 |
TARBP2 over-expression (pCMV-TARBP2-2)_MDA-231 |
| GSM1372081 |
Control (pCMV-GFP-1)_MDA-231 |
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| This SubSeries is part of SuperSeries: |
| GSE49649 |
Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins |
|
| Relations |
| BioProject |
PRJNA245037 |
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