NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE56949 Query DataSets for GSE56949
Status Public on Jul 24, 2014
Title Regulatory consequences of TARBP2 knock-down in Dicer-null MEFs
Organism Mus musculus
Experiment type Expression profiling by array
Summary siRNA-mediated knock-down followed by transcriptomic profiling revealed that silencing of TARBP2 resulted in a significant up-regulation of sRSE-carrying transcripts.
 
Overall design Two independent siRNAs were used to knock down TARBP2 in metastatic Dicer-null cells. The cells were then subjected to transcripome profiling in comparison to mock-transfected cells.
 
Contributor(s) Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF
Citation(s) 25043050
Submission date Apr 21, 2014
Last update date Jun 14, 2018
Contact name Hani Goodarzi
Organization name UCSF
Department Biochemistry and Biophysics
Street address 600 16th St, GH S312D
City San Francisco
State/province CA
ZIP/Postal code 94158
Country USA
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (5)
GSM1372083 TARBP2 knock-down (siTARBP2-1)_DICER-null MEF
GSM1372084 TARBP2 knock-down (siTARBP2-2)_DICER-null MEF
GSM1372085 Control (siControl-1)_DICER-null MEF
This SubSeries is part of SuperSeries:
GSE49649 Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins
Relations
BioProject PRJNA245040

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE56949_RAW.tar 3.1 Mb (http)(custom) TAR
GSE56949_final_processed_matrix.txt.gz 157.4 Kb (ftp)(http) TXT
GSE56949_non-normalized_data.txt.gz 587.4 Kb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap