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Status |
Public on Apr 27, 2014 |
Title |
Expression data from human THP-1 monocytes stimulated with increasing concentrations of arachidonic (AA) or oleic acid (OA). |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Previous data indicated tha AA and OA modify global DNA methylation. This study analyzes the impact of these fatty acids on expression as a complement to array-based DNA methylation data. In this dataset, we include the expression data obtained from THP-1 monocyte stimulated with 1, 10 or 100uM AA or OA for 24h.
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Overall design |
RNA extracted from the same cells used for array-based DNA methylation analysis (see corresponding data in published article) was used to produce expression data by Affymetrix Human Exon 1.0 ST v2 Array
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Contributor(s) |
Silva-Martinez GA, Lund G, Zaina S |
Citation(s) |
27088456 |
Submission date |
Apr 25, 2014 |
Last update date |
Feb 18, 2019 |
Contact name |
Gertrud Lund |
E-mail(s) |
gertrud.lund@cinvestav.mx
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Organization name |
CINVESTAV Irapuato
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Department |
Genetic Engineering
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Lab |
Epigetics
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Street address |
Km 9.6 del Libramiento Norte Carretera Irapuato-León SN
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City |
Irapuato |
State/province |
Guanajuato |
ZIP/Postal code |
36821 |
Country |
Mexico |
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Platforms (2) |
GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
GPL5188 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
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Samples (14)
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GSM1374110 |
cells stimulated with 100uM AA [gene-level] |
GSM1374111 |
cells stimulated with 1uM OA [gene-level] |
GSM1374112 |
cells stimulated with 10uM OA [gene-level] |
GSM1374113 |
cells stimulated with 100uM OA [gene-level] |
GSM1374114 |
unstimulated cells [exon-level] |
GSM1374115 |
cells stimulated with 1uM AA [exon-level] |
GSM1374116 |
cells stimulated with 10uM AA [exon-level] |
GSM1374117 |
cells stimulated with 100uM AA [exon-level] |
GSM1374118 |
cells stimulated with 1uM OA [exon-level] |
GSM1374119 |
cells stimulated with 10uM OA [exon-level] |
GSM1374120 |
cells stimulated with 100uM OA [exon-level] |
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Relations |
BioProject |
PRJNA245472 |