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Status |
Public on Sep 09, 2015 |
Title |
Placental gene expression in intestinal nematode-infected and protein-deficient mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Protein deficiency and intestinal parasite infection during pregnancy impair fetal growth through passage of signals from the maternal environment which signal impairment of fetal growth. The placenta is an important regulator of the transfer of these signals through differential expression of key placental genes. We used microarrays to examine placental gene expression responses to maternal protein deficiency (6% vs. 24% protein) and Heligmosomoides bakeri infection.
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Overall design |
2x2 factorial.
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Contributor(s) |
Starr LM, Koski KG, Scott ME |
Citation(s) |
26475213 |
Submission date |
Apr 25, 2014 |
Last update date |
Feb 21, 2018 |
Contact name |
Lisa M Starr |
E-mail(s) |
lisa.starr@mail.mcgill.ca
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Organization name |
McGill University Health Centre
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Department |
Child Health and Human Development
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Street address |
1001 Boul. Decarie
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City |
Montreal |
State/province |
Quebec |
ZIP/Postal code |
H4A3J1 |
Country |
Canada |
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Platforms (1) |
GPL16570 |
[MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [transcript (gene) version] |
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Samples (12)
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Relations |
BioProject |
PRJNA245451 |