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Series GSE57256 Query DataSets for GSE57256
Status Public on May 03, 2014
Title Expression data from adult lungs isolated from TMEM100-deficient mice
Organism Mus musculus
Experiment type Expression profiling by array
Summary Tmem100 was identified as a downstream gene of BMP9-ALK1 signaling. The signaling has been implicated in hereditary hemorrhagic telangiectasia. This study was designed to identify affected genes in TMEM100-deficiect mice. Tmem100 was inactivated in adult Tmem1002loxP/2loxP;ROSA26+/CreER mice by tamoxifen tereatment. Microarray data was obtained from the lungs isolated from tamoxifen treated control and mutant mice.
 
Overall design Three control mice (Tmem1002loxP/2loxP) and three mutant mice (Tmem1002loxP/2loxP;ROSA26+/CreER) were treated with tamoxifen (two consecutive intraperitoneal injections, 0.1 mg/g of body weight) to activate CreER recombinase. Total RNAs were isolated from lungs 7 days after tamoxifen injection.
 
Contributor(s) Lee YJ, Oh S, Moon E
Citation(s) 25538155
Submission date May 02, 2014
Last update date Jun 14, 2018
Contact name Young Jae Lee
E-mail(s) copg2@hanmail.net
Organization name Gachon University
Department Lee Gil Ya cancer and Diabetes Institute
Lab Developmental Genetics
Street address 155, Gaetbeol-ro, Yeonsu-gu
City Incheon
ZIP/Postal code 406-840
Country South Korea
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (6)
GSM1378008 430: control mouse 1
GSM1378009 431: control mouse 2
GSM1378010 438: control mouse 3
Relations
BioProject PRJNA246087

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE57256_RAW.tar 3.1 Mb (http)(custom) TAR
GSE57256_non-normalized.txt.gz 1.0 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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