|
| Status |
Public on May 15, 2016 |
| Title |
Profling of the Drosophila melanogaster neuronal microRNA transcriptome by small RNA deep sequencing |
| Organism |
Drosophila melanogaster |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
microRNAs (miRNAs) are a class of small non-coding RNAs involved in the coordination and/or fine-tuning of gene expression. As such, miRNAs are thought to be critical cis-acting regulatory factors that control a wide range of physiological processes in the brain. The datasets presented here represent the miRNA transcriptome of the adult and larval Drosophila melanogaster CNS as determined by small RNA deep sequencing (RNA-Seq). They were derived from adult and larval samples explanted from the animal that contain minimal extraneous (non-neuronal) tissues. Here we present a concise summary of our profiling results as well as the original sequencing data. We identify many miRNAs that are expressed at equal levels in both tissues and several that are significantly enriched in the larval and adult brain. Some of these belong to miRNA families with conserved members in mammals. These datasets should provide a good starting point for others interested in characterizing miRNAs with putative functions in Drosophila neurons.
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| Overall design |
The datasets presented here represent the miRNA transcriptome of the adult and larval Drosophila melanogaster CNS as determined by small RNA deep sequencing (RNA-Seq).
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| Contributor(s) |
Barbee SA |
| Citation missing |
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| Submission date |
May 15, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Scott A Barbee |
| E-mail(s) |
scott.barbee@du.edu
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| Phone |
303-871-3582
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| Organization name |
University of Denver
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| Department |
Biological Sciences
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| Street address |
2190 E. ILIFF Ave.
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| City |
Denver |
| State/province |
CO |
| ZIP/Postal code |
80208 |
| Country |
USA |
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| Platforms (1) |
| GPL13304 |
Illumina HiSeq 2000 (Drosophila melanogaster) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA247725 |
| SRA |
SRP042001 |
