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Series GSE59545 Query DataSets for GSE59545
Status Public on Aug 01, 2014
Title NF-kB in Tumor Initiation
Organism Mus musculus
Experiment type Expression profiling by array
Summary p65-/-Ras cells show delayed tumor formation in SCID mice. However, after prolonged latency, tumor formation was observed from these mice. To understand the changes of NF-kB regulated genes before and after tumor formation, RNA from p65+/+Ras, p65+/+RasTumor, p65-/-Ras, p65-/-RasTumor cells were isolated and microarray were performed.
Overall design p65+/+Ras and p65-/-Ras cells were injected into SCID mice. Tumors were removed and put back into tissue culture. RNA was isolated from these cells and microarrays were performed.
Contributor(s) Wang DJ, Ratnam N, Guttridge D, Byrd J
Citation(s) 25263557
Submission date Jul 17, 2014
Last update date Feb 11, 2019
Contact name David Jingxin Wang
Phone 6146884507
Organization name The Ohio State University
Department Comprehensive Cancer Center
Lab Guttridge Lab
Street address BRT536, 460w, 12th Ave.
City Columbus
State/province Ohio
ZIP/Postal code 43210
Country USA
Platforms (1)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Samples (4)
GSM1439179 36R
GSM1439180 36K
GSM1439181 315R
BioProject PRJNA255634

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59545_RAW.tar 40.0 Mb (http)(custom) TAR (of CEL, DCP, TXT)
GSE59545_log2_ratios.txt.gz 393.2 Kb (ftp)(http) TXT
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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