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Series GSE59724 Query DataSets for GSE59724
Status Public on Jul 25, 2014
Title Methylation analysis of locally advanced breast tumors treated with two drugs-doxorubicin and 5-fluorouracil
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Genome wide DNA methylation profiling of locally advanced breast tumors before and after treatment with doxorubicin and 5-fluorouracil Mitomycin C
 
Overall design Bisulphite converted DNA from the 33 paired tumor samples and 9 normal samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2. After preprocessing, seven paired samples treated with doxorubicin were excluded due to low methylation levels, resulting in 26 paired tumor samples that were further analyzed.
 
Contributor(s) Klajic J
Citation(s) 25294903
Submission date Jul 24, 2014
Last update date Jan 07, 2015
Contact name Jovana Klajic
E-mail(s) jovjov@rr-research.no
Organization name OUS/Radium Hospital
Department Genetics
Street address Ullernchauseen 70
City Oslo
ZIP/Postal code 0379
Country Norway
 
Platforms (1)
GPL8490 Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)
Samples (61)
GSM1444409 tumor sample Doxo101a(before)
GSM1444410 tumor sample Doxo101b(after)
GSM1444411 tumor sample Doxo109a
Relations
BioProject PRJNA256041

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59724_RAW.tar 49.3 Mb (http)(custom) TAR (of IDAT)
Processed data included within Sample table

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