|
Status |
Public on Aug 09, 2014 |
Title |
Exosc8-Regulated Genes in Fetal Liver-Derived Erythroid Progenitor Cells |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
Exosc8 and Exosc9 are components of the exosome that establish a barricade to erythroid maturation. Here, we knocked down Exosc8 in fetal liver-derived erythroid progenitor cells to determine the cohort of Exosc8-regulated genes in erythroid cells.
|
|
|
Overall design |
Freshly isolated fetal liver progenitor cells were infected with retrovirus expressing shRNA targeting either luciferase or Exosc8. Total RNA was isolated from these cells after 3 days ex-vivo culture, during which the cells underwent erythroid maturation.
|
|
|
Contributor(s) |
DeVilbiss AW, Bresnick EH |
Citation(s) |
25115889 |
Submission date |
Aug 06, 2014 |
Last update date |
Jul 19, 2017 |
Contact name |
Andrew DeVilbiss |
E-mail(s) |
devilbiss@wisc.edu
|
Phone |
6082656301
|
Organization name |
UW-Madison
|
Department |
Cell and Regenerative Biology
|
Lab |
Emery Bresnick
|
Street address |
1111 Highland Ave, WIMR 4028
|
City |
Madison |
State/province |
WI |
ZIP/Postal code |
53705 |
Country |
USA |
|
|
Platforms (1) |
GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
|
Samples (6)
|
GSM1466217 |
Fetal Liver Erythroid Progenitors - shExosc8 01 |
GSM1466218 |
Fetal Liver Erythroid Progenitors - shExosc8 02 |
GSM1466219 |
Fetal Liver Erythroid Progenitors - shExosc8 03 |
GSM1466220 |
Fetal Liver Erythroid Progenitors - shControl 01 |
GSM1466221 |
Fetal Liver Erythroid Progenitors - shControl 02 |
GSM1466222 |
Fetal Liver Erythroid Progenitors - shControl 03 |
|
Relations |
BioProject |
PRJNA257836 |