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Series GSE60290 Query DataSets for GSE60290
Status Public on Mar 26, 2015
Title Genome-wide analysis of bone marrow-derived macrophage (BMDM) priming by Ifng and Ifnb.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Macrophages are a heterogeneous population of immune cells, which are critical for both the initiation and resolution of inflammation. Pro-inflammatory macrophages can be induced by the Th1 cytokine IFNγ and/or TLR triggers, like LPS. Here, we investigated the effects of IFNγ priming on LPS-induced gene expression in primary mouse macrophages.
 
Overall design To investigate the effect of IFNγ priming on LPS-induced gene expression in macrophages, we stimulated bone marrow-derived macrophages with IFNγ or IFNb for 18 hours and subsequently activated them with LPS for 6 hours.
 
Contributor(s) Scicluna BP, Hoeksma M
Citation(s) 25750432
Submission date Aug 11, 2014
Last update date Jun 14, 2018
Contact name Brendon Paul Scicluna
E-mail(s) b.scicluna@amsterdamumc.nl
Organization name Academic Medical Center
Street address Meibergdreef 9
City Amsterdam
ZIP/Postal code 1105AZ
Country Netherlands
 
Platforms (1)
GPL6885 Illumina MouseRef-8 v2.0 expression beadchip
Samples (15)
GSM1470332 Ctrl_LPS rep1
GSM1470333 Ctrl_LPS rep2
GSM1470334 IFNg_LPS rep1
Relations
BioProject PRJNA257967

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60290_RAW.tar 3.1 Mb (http)(custom) TAR
GSE60290_non_normalized.txt.gz 1.4 Mb (ftp)(http) TXT
Raw data are available on Series record
Processed data included within Sample table

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