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Series GSE60610 Query DataSets for GSE60610
Status Public on Jul 24, 2020
Title In vivo isolated Wnt1-Prim1 Primary, Residual, and Recurrent Tumor Cells
Organism Mus musculus
Experiment type Expression profiling by array
Summary Residual disease represents a major obstacle to the successful treatment of breast cancer, however little is known about the biology of residual tumor cells in vivo. To identify genes differentially expressed in vivo in residual tumor cells compared to primary tumor cells or recurrent tumor cells, we used flow cytometry to isolate GFP-labeled tumor cells from primary, residual, or recurrent tumors grown orthotopically in nu/nu mice. WTA was used to amplify RNA from all tumor cells.
 
Overall design Three timepoints (Primary tumor, residual disease, recurrent tumor) were taken with 3-4 replicates per timepoint.
 
Contributor(s) Pant DK, Ruth JR, Chodosh LA
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Submission date Aug 21, 2014
Last update date Jul 25, 2020
Contact name Dhruv K Pant
E-mail(s) dpant@pennmedicine.upenn.edu
Phone 9083381849
Organization name University of Pennsylvania
Department Cancer Biology
Lab Chodosh
Street address 421 Curie Blvd
City Philadelphia
State/province Pennsylvania
ZIP/Postal code 19104
Country USA
 
Platforms (1)
GPL18802 [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array [mogene20st_Mm_ENTREZG_18.0.0]
Samples (11)
GSM1483660 Wnt1 GFP plus Residual Lesion 1
GSM1483661 Wnt1 GFP plus Residual Lesion 2
GSM1483662 Wnt1 GFP plus Residual Lesion 3
This SubSeries is part of SuperSeries:
GSE60611 Tumor cells that survive oncogenic pathway inhibition exhibit cellular dormancy
Relations
BioProject PRJNA258651

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60610_RAW.tar 110.8 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

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