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| Status |
Public on Aug 10, 2015 |
| Title |
Differential gene expression between female hNAG-1 transgenic and Wt mice in abdominal white adipose tissue (WAT) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To understand the mechanism of extended lifespan in hNAG-1 mice, we used whole genome microarray analysis to examine differential gene expression in abdominal WAT in hNAG-1 mice. Differential category expression analysis may show significant differences between hNAG-1 mice and WT mice in key pathways in the regulation of metabolism and mammalian lifespan.
In addition, To explore the reason why hNAG-1 mice are leaner than Wt littermates.
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| Overall design |
A total of 6 animals from each genotype were used and WAT was extacted from each mouse, we then pooled two sample as one sample for each genotype to be used in microarray experiment.
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| Contributor(s) |
Eling T, Wang X |
| Citation(s) |
25239873 |
| Submission date |
Aug 21, 2014 |
| Last update date |
May 10, 2018 |
| Contact name |
NIEHS Microarray Core |
| E-mail(s) |
microarray@niehs.nih.gov, liuliw@niehs.nih.gov
|
| Organization name |
NIEHS
|
| Department |
DIR
|
| Lab |
Microarray Core
|
| Street address |
111 T.W. Alexander Drive
|
| City |
RTP |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
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| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA258650 |
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