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| Status |
Public on Mar 02, 2015 |
| Title |
Gene expression alteration in chondrocyte by HES1 overexpression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To investigate target molecules of HES1, we transduced GFP or HES1 into mouse chondrocyte cell line ATDC5, and performed the microarray analysis. HES1 overexpression increased inflammation-related genes including Il6 and Il1rl1.
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| Overall design |
We established stable ATDC5 cells overexpressing GFP or HES1 by lentiviral transduction. We harvested mRNA from these cells, and performed microarray analysis.
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| Contributor(s) |
Sugita S, Saito T |
| Citation(s) |
25733872 |
| Submission date |
Aug 25, 2014 |
| Last update date |
Jul 19, 2017 |
| Contact name |
Taku Saito |
| E-mail(s) |
tasaitou-tky@umin.ac.jp
|
| Organization name |
The University of Tokyo
|
| Department |
Orthopaedic Surgery, Faculty of Medicine
|
| Street address |
7-3-1 Hongo, Bunkyo-ku
|
| City |
TOKYO |
| ZIP/Postal code |
113-8655 |
| Country |
Japan |
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| Platforms (1) |
| GPL13912 |
Agilent-028005 SurePrint G3 Mouse GE 8x60K Microarray (Feature Number version) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA259379 |
