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| Status |
Public on Sep 11, 2014 |
| Title |
Gene expression profiles in rat alveolar macrophages exposure to impurity-free single-wall carbon nanotubes |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
To further development of our gene expression approach to assess the effects of manufactured nanomaterials at the transcriptional level, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish characterization of physicochemical properties of impurity-free single-wall carbon nanotubes (SWCNTs), namely, relatively small bundles and a short linear shape (CNT-1) and large bundles and a long linear shape (CNT-2).
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| Overall design |
Two kinds of the impurity-free singlewall carbon nanotubes (SWCNTs), CNT-1 or CNT-2 induced gene expression in rat alveolar macrophages were measured at 24 hours exposure to doses of 0.1mg/mL. The experiments were performed using control for each experiment (n=4).
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| Contributor(s) |
Fujita K, Fukuda M |
| Citation(s) |
25865113 |
| Submission date |
Sep 10, 2014 |
| Last update date |
Apr 16, 2015 |
| Contact name |
Katsuhide Fujita |
| E-mail(s) |
ka-fujita@aist.go.jp
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| Organization name |
National Institute of Advanced Industrial Science and Technology
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| Department |
Research Institute of Science for Safety and Sustainability
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| Street address |
Onogawa 16-1
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| City |
Tsukuba |
| ZIP/Postal code |
3058569 |
| Country |
Japan |
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| Platforms (1) |
| GPL7294 |
Agilent-014879 Whole Rat Genome Microarray 4x44K G4131F (Probe Name version) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA260747 |
